Harris said she had a "frank and constructive" conversation with Netanyahu in which she affirmed Israel's right to defend itself but also expressed deep concern about the high death toll in Gaza over nine months of war and the "dire" humanitarian situation there.

With all eyes on the likely Democratic nominee, Harris largely reiterated Biden's longstanding message that it's time find an endgame to the brutal war in Gaza, where more than 39,000 Palestinians have died. Yet she offered a more forceful tone about the urgency of the moment just one day after Netanyahu gave a fiery speech to Congress in which he defended the war, vowed "total victory" against Hamas and made relatively scant mention of cease-fire negotiations.

"There has been hopeful movement in the talks to secure an agreement on this deal," Harris told reporters shortly after meeting with Netanyahu. "And as I just told Prime Minister Netanyahu, it is time to get this deal done."

Netanyahu met separately earlier in the day with President Joe Biden, who has also been calling on Israel and Hamas to come to an agreement on a U.S.-backed, three-phase deal to bring home remaining hostages and establish an extended cease-fire.

Harris said following her meeting with Netanyahu that Israel's war in Gaza is more complicated than simply about people being supportive of one side or the other.

"Too often, the conversation is binary when the reality is anything but," Harris said.

Harris also condemned Hamas' brutality. White House national security council spokesman John Kirby reiterated the administration position that the militant group that killed some 1,200 on Oct. 7 and kidnapped 250 people from Israel ultimately holds responsibility for the suffering in Gaza and must come to terms with Israel.

Kirby added that gaps between the two sides can be closed "but there are issues that need to be resolved that will require some leadership, some compromise."

With Harris' forceful comments, the administration also appeared to be stepping up pressure on the Israelis to not let the moment pass to get a deal done.

"What has happened in Gaza over the past nine months is devastating. The images of dead children and desperate, hungry people fleeing for safety, sometimes displaced for the second, third or fourth time," Harris said. "We cannot look away in the face of these tragedies. We cannot allow ourselves to become numb to the suffering. And I will not be silent."

Thousands protested Netanyahu's visit in Washington, and Harris condemned those who were violent or used rhetoric that praised Hamas.

Netanyahu, last at the White House when former President Donald Trump was in office, is headed to Florida on Friday to meet with the Republican presidential nominee.

Ahead of the Harris-Netanyahu meeting on Thursday, Trump said at a rally in North Carolina the vice president was "totally against the Jewish people."

Harris has long spoken of her strong support for Israel. The first overseas trip of her Senate career in early 2017 was to Israel, and one of her first acts in office was to introduce a resolution opposing a U.N. Security Council resolution condemning Israel.

She's also spoken of her personal ties to Israel, including memories of raising money as a child to plant trees in Israel, installing a mezuzah near the front door of the vice president's residence in Washington (her husband is Jewish) and her connections to pro-Israel groups including the conservative American Israel Public Affairs Committee and the liberal J Street.

For Harris, the meeting with Netanyahu was an opportunity to demonstrate that she has the mettle to serve as commander in chief. She's being scrutinized by those on the political left who say Biden hasn't done enough to force Netanyahu to end the war and by Republicans looking to brand her as insufficient in her support for Israel.

Harris' last one-on-one engagement with Netanyahu was in March 2021, but she's taken part in more than 20 calls between Biden and Netanyahu.

The conservative Likud Party leader Netanyahu and centrist Democrat Biden have had ups-and-downs over the years. Netanyahu, in what will likely be his last White House meeting with Biden, reflected on the roughly 40 years they've known each other and thanked the president for his service.

"From a proud Jewish Zionist to a proud Irish American Zionist, I want to thank you for 50 years of public service and 50 years of support for the state of Israel," Netanyahu told Biden.

A U.S.-backed proposal to release remaining hostages in Gaza over three phases is something that would be a legacy-affirming achievement for Biden, who abandoned his reelection bid and endorsed Harris. It could also be a boon for Harris in her bid to succeed him.

Following their talks, Biden and Netanyahu met with the families of American hostages.

Netanyahu is trying to navigate his own delicate political moment. He faces pressure from the families of hostages demanding a cease-fire agreement to bring their loved ones home and from far-right members of his governing coalition who demand he resist any deal that could keep Israeli forces from eliminating Hamas.

In his speech to a joint session of Congress on Wednesday, Netanyahu offered a robust defense of Israel's conduct during the war and lashed out against accusations by the International Criminal Court of Israeli war crimes. He made the case that Israel, in its fight against Iran-backed Hamas, was effectively keeping "Americans boots off the ground while protecting our shared interests in the Middle East."

"Remember this: Our enemies are your enemies," Netanyahu said. "Our fight, it's your fight. And our victory will be your victory. "

Netanyahu also derided protesters who massed near the U.S. Capitol on Wednesday, calling them Iran's "useful idiots."

Harris on Thursday said she was outraged that some protesters tagged areas near the U.S. Capitol with pro-Hamas graffiti, expressed support for the militants, and burned a U.S. flag at Union Station.

"Pro-Hamas graffiti and rhetoric is abhorrent and we must not tolerate it in our nation," Harris said in a statement. "I condemn the burning of the American flag. That flag is a symbol of our highest ideals as a nation and represents the promise of America. It should never be desecrated in that way."

Protesters massed near the White House on Thursday chanted, "Arrest Netanyahu," and brought in an effigy of the prime minister with blood on its hands and wearing an orange jumpsuit. A small number of counter-protesters wore Israeli flags around their shoulders.

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AP writer Ashraf Khalil contributed reporting.